Guest Speaker: Nicolas Renier

Title: "Physiological re-wiring of the cerebral vasculature in the adult brain"

After development is completed, the adult cerebral vascular network goes into a quiescent state, in which its 3D structure stays stable. This state is thought to be only broken under pathological conditions. Using whole brain mapping, we show here that shifts in metabolic states in pregnancy or under high fat diet re-engages developmental mechanisms of vascular structural plasticity, with consequences for brain functions.

Date: Thursday, 30 July 2026

Time: 5.00 pm

Location: Large Seminar Room, 8G U1 155

CSD – Center for Stroke and Dementia Research Feodor-Lynen-Str. 17, 81377 Munich

Host: Dominik Paquet, Project: A03

About the speaker: Nicolas Renier is a Research Director at INSERM and group leader at the Paris Brain Institute. His lab has pushed whole-brain imaging technologies using tissue clearing and light-sheet microscopy. This lab aims to understand the rules governing the fine-scale organization and postnatal development of the brain vasculature, how it remodels in physiological contexts and what are the consequences for neuronal functions.